Journal: Psychopharmacology
Article Title: Myocardial infarction sensitizes medial prefrontal cortex to inhibitory effect of locus coeruleus stimulation in rats
doi: 10.1007/s00213-016-4305-y
Figure Lengend Snippet: Example of ECG waveforms collected during LC stimulation in a rat subjected to CAL (a). Three sequential ECG waveforms are shown in each row. Sequential wave forms are shown before start of stimulation (Pre-stim), during stimulation and after stimulation (Post-stim). Note that arrhythmias unique from the prestimulus baseline rhythms develop midway through stimulation and did not revert immediately upon cessation of LC stimulation. bVertical plots indicating percent bigeminy, preventricular contraction (PVC), and ventricular tachycardic (VT) rhythms detected during real or mock LC stimulation in rats subjected to CAL and sham ligation. Symbols represent percent of total waveforms (beats) detected during real or mock stimulation that were of the specified waveform subtype and distinct from any waveform detected during the prestimulus time period for each individual animal. Horizontal bar indicates group mean, and vertical bar is SEM; **P < 0.01
Article Snippet: The ECG pattern recognition software ECG-Auto (EMKA Technologies, Falls Church, VA) was used to detect arrhythmias.
Techniques: Ligation